Visual introduction to CryoEM

Cryo-Electron Microscopy Cryogenic electron microscopy (cryo-EM) is a cryomicroscopy technique applied on samples cooled to cryogenic temperatures (i.e. very cold!.) For biological specimens, the structure is preserved by embedding in an environment of vitreous ice. …

Computing residues per turn in an alpha helix

Single mutation to be modeled I recently had an interesting challenge, that of creating a molecular model of a protein expressed from a gene with a newly identified single amino acid mutation. I (wrongly) assumed …

The Fundamentals of Biochemistry: Interactive Tutorials

The Fundamentals of Biochemistry: Interactive Tutorials from Colorado State University was created by Dr. David Fahrney and edited by Ben Robinson. The 10th edition contains 10 interactive tutorials of the planned 16 chapters. Link: https://bc401.bmb.colostate.edu/ …

Tabular data analysis with R and Tidyverse

Does data analysis feel like the impossible job of “catching the moon?”
Fortunately R and RStudio are great tools to analyze data and illustrate conclusions, while at the same time keeping records and create “live” documents that can be updated with “just one click.”
The material is written in a way that is conducive to “learn by doing” following demonstrations and examples. All code and all necessary materials and files are available and therefore it is possible to learn and acquire proficiency on one’s own with this course content.

Covid-19 protein structures movie

I previously wrote a small booklet using PyMOL to illustrate PyMOL scripting methods and highlight some SARS-CoV-2 (COVID-19) protein structures. These are explored closely in the following movie. The video below depicts COVID-19 protein structures …