Tag: cryo-electron microscopy

Nobel-Winning AlphaFold2 and RosettaFold: Cracking the Protein Folding Mystery

Posted on December 19, 2024

Summary “Explore how David Baker, Demis Hassabis, and John Jumper won the 2024 Nobel Prize in Chemistry for their advances in computer-assisted protein design.” Video: How AI Cracked the Protein Folding Code and Won a Nobel Prize This 22min19 video provides a very good explanation of the origins of the research in protein structure, from …

Visual introduction to CryoEM

Posted on September 7, 2022

Cryo-Electron Microscopy Cryogenic electron microscopy (cryo-EM) is a cryomicroscopy technique applied on samples cooled to cryogenic temperatures (i.e. very cold!.) For biological specimens, the structure is preserved by embedding in an environment of vitreous ice. (See more on the Wikipedia article Cryogenic electron microscopy.) The following links are videos meant to present cryo-EM visually. Unfortunately, …